PC $4.79 Region US
Games Action S.E.M.I. – Side Effects May Include
S.E.M.I. – Side Effects May Include — header artwork
Mature content
Action · Two Horn Unicorn

S.E.M.I. – Side Effects May Include

S.E.M.I. – Side Effects May Include
Mature content
Windows
Very Positive · 86% of 111
DeveloperTwo Horn Unicorn
GenreAction
ControllerFull
$4.79 -40%
Get it at steam
Buy now Chip's verdict · US updated 17 days ago

Well reviewed at 86% positive, and only 0% of the way from its all-time low to full price. It rarely gets better than this.

Why this verdict
Price position between all-time low and full price 0%
All-time low $4.79 · 19d ago
Current discount -40% off $7.99
Player reviews 86% positive of 111
Quality score 86/100
Value score 100/100

Offers

Accepted regional prices from official stores

Official stores (1)
steam
checked 17 days ago Best price
steam, Official, 40% off, $4.79
$4.79 Buy at steam
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Purchase options (1)

Steam packages and bundles that include this game

DLC (3)

Add-on content for this game

Packs and bundles (1)

Multi-item packages that include this game

About this game

What this game is, in the developer's words

S.E.M.I. is a single-player and co-op action platformer with puzzle elements. Play as patients of an unusual clinic, take experimental drugs, interfere with each other, and be ready for chaos and unpredictable side effects!

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here, you and up to 3 of your brainless loyal friends play as patients, fighting staff and other patients while stumbling into all sorts of unexpected situations. Brawls, side-effect pills, and brutal platforming will absolutely challenge your clumsy friends’ hands sense of teamwork. Expect obstacles, puzzles, deadly traps, and rooms where a single wrong move can knock out the entire squad.

Communicate in voice chat and arrange sabotage help your friends pass through rooms, get out of traps and fight with opponents! In your arsenal: close combat, physics, amazing abilities and ... imagination!

Take pills and get abilities:

  • Bipolar force is an invulnerable monster, then a helpless rag!

  • Laser astigmatism — two sights, one laser… Where will he shoot?

  • Stendhal syndrome — are you looking at a painting? Now you're hysterical and destroying everything around you!

  • Alice's syndrome is either tiny or gigantic — have time to adjust!

Madness is near! You and your friends can go crazy and start running, jumping and fighting, and your abilities will become uncontrollable. Do you want to take back control? Take the pills :)

Locations are randomly generated from rooms with changing gravity, traps, moving walls, and other "pleasant" surprises.

After a successful escape, you will receive a medical report: "The patient was stable until he started hitting the guards with a bottle. Diagnosis: Overmotivation" or something worse!

Unlock new costumes and decorations. Let each new escape be more stylish than the previous one!

Will you and your friends be able to escape... or at least not go crazy?

Welcome to the mental hospital! Here, your abilities are a lottery, and your friends can be the most dangerous opponents!

Media

Trailers and screenshots straight from the store page

S.E.M.I. – Side Effects May Include screenshot 1
S.E.M.I. – Side Effects May Include screenshot 2
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S.E.M.I. – Side Effects May Include screenshot 10
S.E.M.I. – Side Effects May Include screenshot 11
S.E.M.I. – Side Effects May Include screenshot 12
S.E.M.I. – Side Effects May Include screenshot 13

Latest news

Recent updates from the game's own feeds

Price intelligence

Accepted price history and the lows that matter

Historical lows
All-time low ATL $4.79 2026-06-27
3-month low $4.79
12-month low $4.79
Current $7.99
Price events From the accepted price history · updates automatically
Jul 9, 2026
Sale ended · back to $7.99
Jun 27, 2026
New all-time low $4.79

S.E.M.I. – Side Effects May Include price history and best deals

S.E.M.I. – Side Effects May Include for PC currently sells from $4.79 at authorized stores. Its all-time low is $4.79, set on 2026-06-27. That is 40% off the $7.99 list price.

Frequently asked questions

Answered from this game's own price and edition data

Should I buy S.E.M.I. – Side Effects May Include now or wait?
Our verdict is buy. The best official price is $4.79, which sits 0% of the way from its all-time low to full price. It rarely gets cheaper than a good sale, so this is a fair time to catch it.
Is $4.79 a good price for S.E.M.I. – Side Effects May Include?
$4.79 sits 0% of the way from the all-time low of $4.79 to the full price, a 40% discount. That is close to the best it has ever been.
Where can I buy S.E.M.I. – Side Effects May Include?
S.E.M.I. – Side Effects May Include is tracked at steam. We only list authorized stores here and always link out with a clean outbound link.
Scores
Steam reviews Very Positive · 86%
86% positive of 111
Media (13)
Tech
ControllerFull
Requirements
System requirements platform
Minimum
Minimum:
  • Requires a 64-bit processor and operating system
  • OS: Windows 10
  • Processor: Intel Core i5 series or Ryzen series
  • Memory: 8 GB RAM
  • Graphics: GTX 960 or AMD R9 290
  • DirectX: Version 11
  • Storage: 3 GB available space
Recommended
Recommended:
  • Requires a 64-bit processor and operating system
  • OS: Windows 11
  • Processor: Intel Core i7 series or Ryzen series
  • Memory: 8 GB RAM
  • Graphics: GTX 1660 or RX6600
  • DirectX: Version 12
  • Storage: 3 GB available space
Minimum
Minimum:
    Recommended
    Recommended:
      Minimum
      Minimum:
        Recommended
        Recommended:
          Achievements (9)
          StoryMode_Stages_1 11.9%
          StoryMode_Stages_2 4.5%
          EscapeMode_Diagnoses_01 3.3%
          StoryMode_Stages_3 2.0%
          StoryMode_Stages_All_Medals 0.2%
          EscapeMode_Diagnoses_05 0.1%
          EscapeMode_Diagnoses_10 0.0%
          EscapeMode_Diagnoses_20 0.0%
          Facts
          DeveloperTwo Horn Unicorn
          PublisherTwo Horn Unicorn
          GenresAction · Indie
          ModesMulti-player · Single-player · Co-op
          Links
          Ratings
          dejus14
          igrs18
          steam_germany12
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